Product Name：Tetramethylenedimaleimide
Synonymous：BMB Crosslinker;1,1'-(1,4-Butanediyl)bis[1H-pyrrole-2,5-dione]; 1,4-Bis(maleimide)butane; 1,4-Bis(maleimido)butane; 1,4-Di(maleimido)butane; 1-[4-(2,5-Dioxopyrrol-1-yl)butyl]pyrrole-2,5-dione; N,N'-1,4-Butylenebismaleimide; N,N'-Tetramethylenebis[maleimide]; N,N'-Tetramethylenedimaleimide; Tetramethylenebismaleimide;
CAS：28537-70-4
3) Green, Nora S.; Reisler, Emil; Houk, K. N.; Protein Science 2001, 10(7), 1293-1304, DOI: 10.1110/ps.51201 ; Quantitative evaluation of the lengths of homobifunctional protein cross-linking reagents used as molecular rulers
4) Cheronis, John C.; Whalley, Eric T.; Nguyen, Khe T.; Eubanks, Shad R.; Allen, Lisa G.; Duggan, Matthew J.; Loy, Sharon D.; Bonham, Kathryn A.; Blodgett, James K.; J. Med. Chem. 1992, 35(9), 1563-1572, DOI: 10.1021/jm00087a010 ; A new class of bradykinin antagonists: synthesis and in vitro activity of bissuccinimidoalkane peptide dimers
Synonymous：BMB Crosslinker;1,1'-(1,4-Butanediyl)bis[1H-pyrrole-2,5-dione]; 1,4-Bis(maleimide)butane; 1,4-Bis(maleimido)butane; 1,4-Di(maleimido)butane; 1-[4-(2,5-Dioxopyrrol-1-yl)butyl]pyrrole-2,5-dione; N,N'-1,4-Butylenebismaleimide; N,N'-Tetramethylenebis[maleimide]; N,N'-Tetramethylenedimaleimide; Tetramethylenebismaleimide;
CAS：28537-70-4
Basic Info
| M.F. | C12H12N2O4 | M.W. | 248.23468 | ||
| Appearance | |||||
Properties
1) It is soluble in DMF and DMSO
2) Sealed at room temperature
2) Sealed at room temperature
Appications
1) It can be used as crosslinking agent
Characterization
Reference
1) Feast, William J.; Put, J.; De Schryver, F. C.; Compernolle, F. C.; Organic Mass Spectrometry 1970, 3(4), 507-517, DOI: 10.1002/oms.1210030408 ; Mass spectra of maleimides, isomaleimides, bis-maleimides, bis-isomaleimides and the intramolecular photocyclization products of bis-maleimides
2) Matuszak, Nicolas; Muccioli, Giulio G.; Labar, Geoffray; Lambert, Didier M.; J. Med. Chem. 2009, 52(23), 7410-7420, DOI: 10.1021/jm900461w ; Synthesis and in Vitro Evaluation of N-Substituted Maleimide Derivatives as Selective Monoglyceride Lipase Inhibitors