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1,6-Bismaleimidohexane

1,6-Bismaleimidohexane

CAS NO.:4856-87-5Formula:C14H16N2O4Weight: 276.28784
Product Name:N,​N'-​Hexamethylenedimalei​mide
Synonymous:BMH Crosslinker; GMBMI; GP 207R; 1,​6-​BMH;;Hexamethylenediamine bismaleimide; N,​N'-​Hexamethylenebis[mal​eimide]​; 1,​1'-​hexane-​1,​6-​diylbis(1H-​pyrrole-​2,​5-​dione)​; 1,​6-​Bismaleimidehexane; 1,​6-​Bismaleimidohexane; 1,​6-​Dimaleimidohexane; 1,​6-​Hexamethylenebis[mal​eimide]​; 1,​6-​Hexanediylbismaleimi​de; 1,​6-​Maleimidohexane; 1-​[6-​(2,​5-​Dioxopyrrol-​1-​yl)​hexyl]​pyrrole-​2,​5-​dione;
CAS:4856-87-5
Basic Info
M.F. C14H16N2O4 M.W. 276.28784
Appearance  
Properties
1)   It is soluble in DMF and DMSO
2)   Sealed at room temperature
Appications
1) It can be used as crosslinking agent
Characterization
HNMR
NA
MS
NA
FTIR
NA
HPLC
NA
Reference
1) Schmidt C J; Thomas T C; Levine M A; Neer E J; J. biological chem. 1992, 267(20), 13807-13810, Specificity of G protein beta and gamma subunit interactions
2) Costantini, Paola; Belzacq, Anne-Sophie; Vieira, Helena L. A.; Larochette, Nathanael; De Pablo, Manuel A.; Zamzami, Naoufal; Susin, Santos A.; Brenner, Catherine; Kroemer, Guido; Oncogene 2000, 19(2), 307-314, DOI: 10.1038/sj.onc.1203299 ; Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-​2-​independent permeability transition pore opening and apoptosis
3) Green, Nora S.; Reisler, Emil; Houk, K. N.; Protein Science 2001, 10(7), 1293-1304, DOI: 10.1110/ps.51201 ; Quantitative evaluation of the lengths of homobifunctional protein cross-​linking reagents used as molecular rulers
4) Zhang, Huan; Gao, Fei; Cao, Xiaodong; Li, Yanqun; Xu, Yuanze; Weng, Wengui; Boulatov, Roman; Angew. Chem., Int. Ed. 2016, 55(9), 3040-3044, DOI: 10.1002/anie.201510171 ; Mechanochromism and Mechanical Force-​Triggered Cross-​Linking from a Single Reactive Moiety Incorporated into Polymer Chains